Application of eye tracking technology in screening for cognitive impairment:an integrative review

ZHANG Shifang; HUANG Xiuxiu; AN Ran; XIAO Weizhong; WAN Qiaoqin

doi:10.3969/j.issn.1671-315x.2025.09.007

Abstract：Objective To understand the current research status of eye tracking for the assessment and screening of cognitive impair-ment,and to provide reference and guidance for the future development of eye tracking-based assessment or screening tools.Methods Ac-cording to the integrated review framework proposed by Whittemore relevant studies were searched in The Cochrane Library,PubMed,Em-base,Web of Science,PsycINFO,CNKI,Wanfang and VIP databases.The literature search was conducted from the database inception to Janu-ary 20,2025.Literature screening was carried out according to the inclusion criteria,data,including the eye-tracking tasks,screening perform-ance,was extracted and synthesized.Results Ultimately,18 literatures were included in the study,and the cognitive dimensions were mainly executive function and memory function.Eye movement tracking tasks include scanning,stable tracking,visual search,and exploratory eye traj-ectory movement examination.The screening duration includes short duration(3 to 5 minutes)and long duration(20 to 60 minutes).The con-struction methods of the screening model included in the study were index result,regression models and machine learning.The AUC range of screening performance was 0.620～0.975,which was related to the eye movement task and the model construction method.Conclusion The included studies primarily assesed single-damain cognitive function.The screening performance is related to the screening tasks and model construction methods.It is suggested that future research can further analyze the effectiveness of different eye movement tasks and indi-cators,integrate different tasks,and construct screening tools that can evaluate overall cognitive function to screen for cognitive impairment more effectively.