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Inaugural EditorialBaofeng YangPrevention and control measures of the major cold-region diseases(hypertension)in ChinaZhenwei Pan, Yong Zhang, Tengfei Pan, Haihai Liang, Baofeng YangHydrogen sulfide,microbiota,and sulfur amino acid restriction dietRui WangDiscussion on the model of community management of chronic diseases in cold areasRui Jiang, Yuquan Zhao, Yongchen WangTraditional Chinese medicine in the treatment of high incidence diseases in cold areas:the thrombotic diseasesXueqing Tang, Xin Liu, Monayo Seth Mikaye, Hongrui Zhao, Yong ZhangTridepsides from the endophytic fungus colletotrichum gloeosporioides associated with a toxic medicinal plant tylophora ovataSen-Feng Sun, Shao Zhu, Hai-Yan Cao, Yun-Bao Liu, Shi-Shan YuAblation of apoptosis-stimulating of p53 protein 1 protects mice from acute hepatic injury and dysfunction via NF-κB pathway in CCl4-induced hepatotoxicityTolessa Muleta Daba, Xiang Huang, Timur Yagudin, Ying Yang, Jiangang Wang, Xiaoyu Fu, Yue Zhao, Haiyu Gao, Yang Zhou, Zhenwei Pan, Xiangyu ZhongCOLD in Medicine is More Than Just Low Temperature…… 