Effect of early-pregnancy ultrasound indices on uterine receptivity at 6 months after treatment in women with Cesarean scar pregnancy
GUO Jing
YANG Bo
CAI Yuru
Abstract：Objective To evaluate the effect of early-pregnancy ultrasound indices on uterine receptivity at 6 months after treatment in women with Cesarean scar pregnancy(CSP).Methods A total of 127 women with CSP admitted from January 2020 to December 2024 were enrolled.Based on the uterine receptivity score at 6 months after treatment,patients were divided into an abnormal group(n=37)and a normal group(n=90).Demographic characteristics and early-pregnancy ultrasound indices were compared between groups.Receiver operating characteristic(ROC)curve analysis assessed the predictive value of two quantitative Doppler indices—trophoblastic blood flow resistance index(RI)and uterine artery pulsatility index(PI)—for poor uterine receptivity at 6 months.Multivariable logistic regression was used to evaluate the independent effects of early-pregnancy ultrasound indices on uterine receptivity.Results Significant between-group differences were observed in age,interpregnancy interval,number of prior CSPs,history of uterine cavity surgery,scar myometrial thickness,gestational sac position and shape,thickness of the gestational sac-bladder myometrial layer,trophoblastic blood flow RI,and uterine artery PI(all P<0.05).ROC analysis showed that trophoblastic blood flow RI and uterine artery PI had good predictive value for poor uterine receptivity,with area under the curve(AUC)values of 0.84 and 0.82,respectively;optimal cutoffs were≤0.43 for RI and≤2.35 for PI.Multivariable logistic regression identified older age and prior uterine cavity surgery as risk factors for impaired uterine receptivity at 6 months,while scar myometrial thickness≥3.0 mm,higher trophoblastic blood flow RI,and higher uterine artery PI were protective factors.Conclusion Among early-pregnancy ultrasound indices,trophoblastic blood flow RI and uterine artery PI provide useful pre-assessment information for predicting poor uterine receptivity at 6 months after treatment in women with CSP.Increased scar myometrial thickness(≥3.0 mm),higher trophoblastic RI,and higher uterine artery PI have protective effects on uterine receptivity.
Keywords：early pregnancyultrasound indicescesarean scar pregnancyuterine receptivity
Publication Date：2026-01-26
Online Publishing Date：2026-03-17(First online date of this platform, not the publication date of the document)
Pages：4( 49-52 )