Association between maternal glucose-lipid metabolism and neonatal birth weight
WEI Juping
BAI Liwei
LU Qiang
Abstract：Objective To examine the relationship between maternal glucose-lipid metabolic parameters and neonatal birth weight.Methods Totally 642 pregnant women with single fetus attending routine antenatal check-ups at Qinhuangdao Maternal and Child Health Hospital from December 2017 to December 2018 were categorized into normal birth weight,macrosomia,and low birth weight groups according to neonatal birth weight.Baseline characteristics and maternal metabolic indices during pregnancy were compared.Correlations between maternal metabolic indices and birth weight were assessed.Multiple linear regression was used to identify independent determinants of birth weight.Results Maternal height,pre-pregnancy weight and body mass index(BMI),as well as fasting blood glucose(FBG),triacylglycerol(TG),and glycated hemoglobin(HbA1c)in early pregnancy were each positively correlated with neonatal birth weight(all P＜0.05).In regression analysis,pre-pregnancy BMI as well as FBG and TG in early pregnancy remained significant independent predictors of birth weight(all P＜0.05).Conclusion Pre-pregnancy BMI,as well as FBG,HbA1c,and TG in early pregnancy,are independent risk factors for neonatal birth weight.
Keywords：glucose-lipid metabolismneonatal birth weightmacrosomialow birth weight
Publication Date：2025-12-26
Online Publishing Date：2026-01-15(First online date of this platform, not the publication date of the document)
Pages：4( 2089-2092 )