Effects of high-intensity focused ultrasound on pregnancy outcomes of uterine myoma and adenomyosis

WANG Jiyuan; GUO Zhankun; ZHANG Xue

doi:10.3969/j.issn.1002-7386.2024.20.020

Abstract：Objective To investigate the effects of the high-intensity focused ultrasound(HIFU)on the pregnancy of patients with uterine fibroids and adenomyosis who have fertility requirements,and to investigate the effects of HIFU on the ongoing pregnancy.Methods From October 2013 to April 2017,outpatients with uterine fibroids and adenomyosis who had fertility requirements and treated with HIFU were included.Uterine size,lesion volume and symptoms improved of uterine fibroids before and after treatment of HIFU were retrospectively analyzed.The menstrual status,dysmenorrhea,lesion volume changes of uterine adenomyosis before and after treatment of HIFU were investigated.The clinical data of 29 patients with uterine fibroids and 16 cases of adenomyosis who got pregnant after HIFU were analyzed for their pregnancy and pregnant outcome.Results At 6 months of HIFU treatment,the uterine volume and uterine fibroids of patients with uterine leiomyoma were significantly smaller than those before treatment(P＜0.05).The clinical symptoms were significantly improved with a high improvement rate.The menstrual period,menstrual flow,dysmenorrhea score,adenomyoma volume were significantly improved after treatment(P＜0.05).In 45 cases of ongoing pregnancy,41 cases have been delivered successfully,with good fetal growth and development.Serious complications of pregnancy were not reported.Conclusion HIFU for treating uterine fibroids and adenomyosis is effective and safe that can improve the pregnancy rate without causing adverse events of pregnancy and childbirth.HIFU is an ideal choice for patients with uterine fibroids and adenomyosis who have fertility requirements,which is worthy of clinical promotion.