Effect of oral carbohydrate combined with enhanced recovery after surgery on perioperative rehabilitation of patients with colorectal cancer
YUE Lei
DUAN Jiawen
ZHANG Zhisheng
Abstract：Objective To investigate the effect of oral carbohydrate combined with enhanced recovery after surgery(ERAS)on perioperative rehabilitation of patients with colorectal cancer(CC).Methods A total of 73 CC patients admitted from January 2019 to January 2021 were randomly divided into oral carbohydrate group(group A,36 cases)and oral carbohydrate+ERAS mode group(group B,37 cases).The perioperative data of the two groups were introduced in SPSS 21.0 software to compare the perioperative rehabilitation efficacy between the two groups.Results Motilin(MTL)at day 1 and day 3 postoperatively in group A was significantly lower than that of group B,and MTL at day 7 was significantly higher(P＜0.05).Insulin growth factor 1(IGF-1)at day 1 postoperatively in group A was significantly lower than that of group B,and IGF-1 at day 3 and day 7 was significantly higher(P＜0.05).Diamine oxidase(DAO)at day 1 and day 3 postoperatively in group A was significantly higher than that of group B(P＜0.05).There were significant differences in MTL,IGF-1 and DAO before and after treatment between groups(P＜0.05).The subjective comfort scores of thirst,hunger and anxiety in group A were significantly higher than those of group B(P＜0.05).The total postoperative complication rate in group A was significantly higher than that of group B(27.78％vs 13.51％,P＜0.05).Conclusion Oral carbohydrate combined with ERAS can effectively promote the recovery of gastrointestinal function in CC patients alleviate the injury of intestinal mucosal barrier,improve subjective comfort,and reduce postoperative complications.
Keywords：carbohydrateenhanced recovery after surgerycolorectal cancerperioperative rehabilitation
Publication Date：2024-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1196-1199 )