Application of acellular dermal matrix patch in palatorrhaphy
Abstract：[Abstrsct] Objective To observe the effects of acellular dermal matrix patch on speech sound after palatorrhaphy. Methods A total of 88 patients with cleft palate were randomly divided into 2 groups,44 patients in control group were treated by two gram flap method combined with levator palatine velum reconstruction, however, the other 44 patients in experimental group,on the basis of control group, were treated by acellular dermal matrix patch covering the exposed bone surface and bilateral relaxation incision. After treatment the postoperative velopharyngeal closure rate,excellent rate of speech articulation by subjective assessment,the longest time of blowing bubble test were observed and compared between the two groups. Results The postoperative velopharyngeal closure rate in experimental group was 79. 55% (35/44),which was significantly higher than that [45. 45% (20/44)] in control group (P＜0. 05). The longest time of blowing bubble test was prolonged in both groups, as compared with that before treatment , moreover, the longest time of blowing bubble test in experimental group was significantly longer than that in control group (P＜0. 05). In addition the excellent rate of speech articulation by subjective assessment in experimental group was significantly higher than that in control group (P＜0. 05). The formant frequency value before a,I phonation in experimental group was significantly higher than that in control group ( P＜0. 05). Conclusion The acellular dermal matrix patch used in cleft palate repairing can improve postoperative phonation of patients,which is an effective and safe method,thus, it is worthy of further promotion in clinical practice.
Keywords：cleft palatespeech sound recoverydecellularization dermis groundsubstance patchtreatment outcome
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1961-1963,1968 )