Therapeutic effects of ultrasound-guided sympathetic nerve block combined with traditional Chinese medicine onrefractory angina pectoris

doi:10.3969/j.issn.1002-7386.2018.11.013

Abstract：Objective To investigate the clinical curative effects of ultrasound-guided sympathetic nerve block combined with traditional Chinese medicine on refractory angina pectoris. Methods Sixty patients with refractory angina pectoris who were diagnosed and treated in our hospital from October 2015 to January 2017 were randomly divided into research group ( n =30 ) and control group ( n =30 ) . The patients in research group were treated by ultrasound-guided sympathetic nerve block combined with traditional Chinese medicine,however, the patients in control group were treated by conventional blind sympathetic nerve block anesthesia combined with traditional Chinese medicine. After treatment, the therapeutic effects were evaluated. Moreover, the attack frequency and duration of angina pectoris before and after treatment were recorded. In addition, the changes of hemodynamic indexes and myocardial enzyme levels were observed and compared between two groups. Results The efficient rate ( 76. 67％) and total effective rate in research group were 76. 67％, 93.33％,respetively,which were significantly higher than those (40. 00％,73. 33％,respectively) in control group (P <0. 05). After treatment the attack frequency and duration of angina pectoris were significantly decreased in both groups, moreover, which in research group were significantly lower than those in control group (P < 0. 05). In addition, the hemodynamic indexes including blood viscosity high shear viscosity, low shear viscosity of whole blood viscosity, fibrinogen and plasma viscosity as well as myocardial enzyme indexes including cTnI, LDH, CK-MB in research group were superior to those in control group (P <0. 05). Conclusion The ultrasound-guided sympathetic nerve block combined with traditional Chinese medicine can obtain satisfactory therapeutic effects on refractory angina pectoris, which can improve the attack frequency and duration of angina pectoris, and improve the indexes of hemodynamics and myocardial enzyme,therefor, which is worth using widely in clinical practice.