The application of hs CRP detection in diagnosis of bacterial and mycoplasma infection in children

doi:10.3969/j.issn.1002-7386.2018.09.007

Abstract：Objective To evaluate the application value of three indexes including high sensitivity C-reactive protein (hsCRP),white blood cell count and neutrophil ratio in diagnosis of bacterial infection and mycoplasma infection in children. Methods A total of 135 children patients with infection who were treated in our hospital from January 2011 to October 2016 were enrolled as case group, in whom, there were 97 cases of bacterial infection (group A) and 38 cases of mycoplasma infection (group B),at the same time,60 healthy children who underwent physical examination in our hosptital were enrolled as control group (group C). The diagnostic value of three indexes including hsCRP, white blood cell count and neutrophil proportion in diagnosis of bacterial and mycoplasma infection was evaluated.Result Before treatment, there were significant differences in hs CRP,white blood cell count and neutrophil proportion among the three groups(P<0.05). The levels of hs CRP and white blood cell count in group A were significantly higher than those in the other two groups,however,the levels of neutrophils proportion in group B were significantly higher than those in group A and group C.After 7 -day treatment, the levels of hsCRP and white blood cell count were significantly decreased,as compared with those before treatment(P<0.05). The diagnostic value of hsCRP in diagnosis of bacterial infection was the best. Conclusion HsCRP and white blood cell count have a certain guiding significance in diagnosis and observation of therapeutic effects in children with bacterial infection, comparatively speaking, hs CRP has more important diagnostic value. However, neutrophil proportion has a certain significance in diagnosis of mycoplasma infection.