Therapeutic effects of arthroscopic synovectomy combined with postoperative 3-D conformal radiotherapy on pigmented villonodular synovitis
Abstract：Objective To observe the therapeutic effects of arthroscopic synovectomy combined with postoperative three dimensional (3-D) conformal radiotherapy on knee joint diffuse pigmented villlonodular synovitits (DPVNS).Methods Eighteen patients with knee joint DPVNS were treated by 3-D conformal radiotherapy after arthroscopic synovectomy,in whom,16 patients were treated with dose of 36 Gy/18 F,however,the other two patients were treated with dose of 40 Gy/20 F.Results The 18 patients were followed up for 6~113 months(median time:49 months).The local control rate was 100% (18/18),and local relapse rate was 0%. The radiotherapy tolerance of patients was well,without ≥grade 2 acute/late radiation damage.Among 18 patients,there were 5 cases(28%) of excellent knee joint function and 13 cases(72%) of good knee joint function.Conclusion The postoperative 3-D conformal radiotherapy after arthroscopic synovectomy is effective and safe for patients with DPVNS,which can effectively prevent postoperative relapse.
Keywords：pigmented villonodular synovitisdiffuse formthree dimensional conformal radiotherapyknee joint
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 870-873 )