Significance of combined detection of myocardial enzymes with C-reactive protein in evaluation of disease condition of neonatal pneumonia
Abstract：Objective To investigate the significance of combined detection of myocardial enzymes with C-reactive protein in evaluation of disease condition of neonatal pneumonia.Methods Forty-nine neonates with pneumonia were enrolled as observation group,at the same time,the other 48 healthy mature neonates were enrolled as control group. The serum levels of CK, CK-MB, AST,LDH and CRP were detected and compared between two groups. Results The serum levels of myocardial enzymes indexes and CRP in observation group were significantly higher than those in control group (P<0.05). The serum levels of myocardial enzymes indexes and CRP in severe case of observation group were significantly higher than those in control group (P <0.05). Moreover the serum levels of myocardial enzymes indexes and CRP in patients with bacterial and mycoplasma pneumonia were significantly lower than those of patients with viral pneumonia (P<0.05). The serum levels of CK,AST,CK-MB, AST,LDH in patients with bacterial pneumonia were significantly lower than those of patients with mycoplasma pneumonia (P<0.05). In addition the serum levels of CRP in patients with bacterial pneumonia were significantly higher than those of patients with mycoplasma pneumonia and those of patients with viral pneumonia (P<0.05). Besides the serum levels of myocardial enzymes indexes and CRP in patients with neonatal pneumonia at acute stage were significantly higher than those of patients with neonatal pneumonia at convalescence stage(P<0.05).Conclusion The increase of myocardial enzymes spectrum is positively correlated with the disease condition of neonatal pneumonia. The detection of myocardial enzymes is helpful to early detect the damage of myocardium and evaluate the degree of damage, moreover,combined detection with CRP is beneficial to judge correctly bacteria pneumonia and non-bacterial pneumonia.
Keywords：neonatal pneumoniamyocardial damagemyocardial enzymes spectrumC-reactive protein
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 562-565 )