The directive significance of combination detection of D-dimer and femoral artery color dopplar ultrasound in treatment and prognossis evaluation of patients with lower limb venous thrombosis
HUANG Shuhui
CHEN Tingcai
CHEN Manqing
Abstract：Objective To investigate the directive significance of combination detection of D-dimer and femoral artery color dopplar ultrasound in treatment and prognossis evaluation of patients with lower limb venous thrombosis.Methods One hundred and seventy patients with lower limb venous thrombosis who were treated in our hospital were enrolled in the study. These patients were examined by D-dimer combined with femoral artery color Dopplar ultrasound. The patients with the concentration of plasma D-dimer >1,000μg/L were regarded as positive patients. The patients whose examination results of color Doppler ultrasound were negative and the detection results of D dimer were positive should have a second detection.All the patients received lower limb venography detection. Results The levels of D-dimer in patients with lower limb venous thrombosis complicated by pulmonary embolism were significantly higher than those of patients with simple lower limb venous thrombosis (P<0.05).The positive rate of D dimer and D-dimer levels before and after thrombolysis in patients with mixed type lower limb venous thrombosis were significantly higher than those of patients with peripheral and central type lower limb venous thrombosis (P<0.05).The combination detection of color Dopplar ultrasound and plasma levels of D-dimer could increase the sensitivity of detecting the central type,peripheral type and mixed type lower limb venous thrombosis.Conclusion The combination detection of color Dopplar ultrasound and plasma levels of D-dimer can increase the specificity and sensitivity of detection of lower limb venous thrombosis,which has directive significance in the treatment and prognosis evaluation of patients with lower limb venous thrombosis.
Keywords：D-dimercolor Dopplar ultrasoundlower limb deep venous thrombosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 515-517,522 )