Correlation between shear wave velocity of thyroid tissue and thyroid-stimulating hormone in patients with primary hyperthyroidism and its clinical significance
Abstract：Objective To explore the correlation between shear wave velocity (SWV) of thyroid tissue and thyroid stimulating hormone (TSH) in patients with primary hyperthyroidism and its clinical application value.Methods Forty-three patients who were diagnosed as primary hyperthyroidism (PTH group) in our hospital and 45 healthy subjects (control group) were enrolled in the study.The SWV of thyroid tissue in all the subjects was measured by acoustic radiation pulse imaging (ARFI).The serum levels of TSH were detected,and the correlation between SWV and TSH was analyzed by repeated measurement analysis of variance (ANOVA).The ROC curve was used to analyze the diagnostic efficacy of SWV.Results The SWV and serum levels of TSH in PHT group were (1.72 ± 0.08) m/s and (1.26 ± 0.36) mU/L,respectively,which were significantly lower than those [(2.22 ± 0.08) m/s and (2.38 ± 0.47) mU/L] in control group (P ＜ 0.05).The correlation analysis showed that SWV was positively correlated to TSH (r =0.585,P ＜ 0.05).Moreover ROC curve showed that SWV had diagnostic efficacy at a certain extent,with its AUC being 0.948.Conclusion The thyroid tissue elasticity is positively correlated to TSH in patients with primary hyperthyroidism,moreover,SWV has a certain diagnostic efficacy,therefor,ultrasound elasticity imaging can be regarded as an assessment method during treatment and follow-up of patients with primary hyperthyroidism.
Keywords：primary hyperthyroidismShear wave velocitythyroid stimulating hormone
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 401-404 )