The risk factors related with incidence of hypoglycemia in patients with diabetes mellitus after intensive insulin therapy
LIANG Caihong
XIONG Wanjun
Abstract：Objective To investigate the incidence rate of hypoglycemia and its risk factors in patients with diabetes mellitus after intensive insulin therapy.Methods A total of 265 patients with type 2 diabetes mellitus who were treated in our hospital from January 2015 to December 2015 were enrolled in the study.These patients were treated by intensive insulin therapy,then,patient's medical history was collected,biochemical indicators and blood glucose levels were detected,moreover,the incidence rate of hypoglycemia and its risk factors were analyzed.Results Sixty-eight patients had hypoglycemia,with incidence rate of hypoglycemia being 25.66%.The multi-factor Logistic regression analysis showed age [OR=3.46,95% CI (1.58~8.24)],course of disease [OR=2.67,95% CI (1.87~5.36)],creatinine [OR=1.24,95% CI (1.03~1.64)],BMI [OR=0.56,95% CI (0.33~0.87)] and fasting C peptide were the independent risk factors of incidence of hypoglycemia.Conclusion The blood glucose monitoring should be strengthened when patients with diabetes mellitus are treated by intensive insulin therapy,especially for the patients with older age,longer disease course,higher creatinine,lower BMI and lower fasting C peptide levels,so as to prevent the incidence of hypoglycemia.
Keywords：intensive insulin therapyhypoglycemiarisk factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1461-1463,1467 )