Early efficiency evaluation of 3.0T MRI on uterine fibroids after treated by high-intensity focused ultrasound
Abstract：Objective Using 3.0T MRI unenhanced and enhanced MRI scanning to evaluate the early therapeutic effects of high-intensity focused ultrasound (HIFU) on uterine fibroids.Methods Thirty-three patients with uterine fibroids including 20 cases of solitary uterine fibroid and 13 cases of multiple uterine fibroids,a total of 59 uterine fibroids,whose mean age was (34.3±8.7) years,were enrolled in the study.All the patients underwent unenhanced MRI scan and enhanced MRI scan before HIFU and after HIFU to observe and calculate quantitatively the signal value of T2WI fat suppression, T2WI, unenhanced and enhanced T1WI of uterine fibroids and uterine wall,moreover, to calculate the maximum ablation area of fibroids and to evaluate the therapeutic effects.Results The 59 fibroids did not appear enhancement of ablation zone in T1W1 enhanced scan sequence after HIFU,with average ablation rate being 70.9%.The signal value of enhanced T1WI was significantly decreased,as compared with that before HIFU (P<0.01).The postoperative ablation zone showed different degree high signals in unenhanced T1 plain scan image,and the ablation zone range displayed unclearly in T2 image,and T2 signal value was significantly increased,as compared with that before HIFU (P<0.01).The high signal area of T1WI after postoperative MRI scan was smaller than that in the ablation area of enhanced MRI scan (P<0.01).The area of increased signal of enhanced T1WI was closely correlated to the ablation area of enhanced MRI scan (r=0.94).The signal intensity in muscle wall in solitary myoma group was significantly decreased after HIFU,as compared with that before HIFU (P<0.05).The signal intensity of T2WI fat suppression scan in muscle wall in multiple fibroids group was obviously decreased (P<0.05).There was no significant difference in the signal intensity of T2WI fat suppression scan in muscle wall at different distances to fibroids (<0.5cm,0.5~1.0cm,>1.0cm) among solitary uterine fibroid groups.Conclusion The 3.0T MRI enhanced scan can show the fibroid ablation zone directly and accurately, moreover, the high signal area of postoperative T1WI can display necrosis area of fibroids after HIFU and can evaluate the ablation range.
Keywords：[Key Words] MRIenhanced scanhigh-intensity focused ultrasounduterine fibroids
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1331-1334 )