Study of correlation between FA value of precentral gyrus and postcentral gyrus during normal brain aging and age as well as sex

doi:10.3969/j.issn.1002-7386.2017.07.003

Abstract：Objective To investigate the correlation between FA value of precentral gyrus and postcentral gyrus during normal brain aging and age as well as sex by using MR diffusion tensor imaging (DTI).Methods One hundred and twenty healthy right handedness volunteers ,according to gender and age ,were divided into young female group and young male group (≤44 years) as well as older female group and older male group ( >45 years).All the volunteers were examined by magnetic resonance imaging (MRI) and DTI, with determining the regions of interest artificially [ROI:(18 ±2)mm2].The FA values of left precentral gyrus ,right precentral gyrus,left postcentral gyrus,right postcentral gyrus were measured by the machine automatically ,measuring 3 times and taking their average .The differences of FA value among different sex and age groups were observed and compared ,moreover , the correlation between FA value of precentral gyrus ,postcentral gyrus and age as well as sex was analyzed .Results There were significant differences in the FA values of left precentral gyrus , right precentral gyrus,left postcentral gyrus,right postcentral gyrus among different age groups with same gender ( P <0.05). However there were no significant differences in the FA values of left precentral gyrus ,right precentral gyrus ,left postcentral gyrus,right postcentral gyrus between different sex groups with same age ( P >0.05).Conclusion During normal brain aging,the FA values of left precentral gyrus ,right precentral gyrus,left postcentral gyrus,right postcentral gyrus are negatively correlated with age ,namely the FA values are decreased with the age increasing .However there are no significant differences in the FA values of left or right precentral gyrus and precentral gyrus between female and male .