Correlation between blood pressure variability, blood pressure mroning surge and atherosclerosis in patients w ith cerebral infarction complicated by hypertension
ZHOU Jianchang
Abstract：Objective To investigate the correlation between blood pressure variability ,blood pressure morning surge and atherosclerosis( AS) in patients with cerebral infarction complicated by hypertension .Mtehods One hundred and thirty-two patients with cerebral infarction complicated by hypertension who were admitted and treated in our hospital from January 2015 to August 2016 were enrolled in the study .These patients were examined by color Doppler ultrasound to measure intimae-media thickness ( IMT) of carotid artery .All the patients were divided into 3 groups according to IMT:20 patients in normal IMT group ,56 patients in IMT thickening group and 56 patients in IMT plaque group ,and the patients in the latter two groups were regarded as AS .Moreover according to 24-hour ambulary blood pressure monitoring results the 132 patients were divided into the non-morning surge group ( n =49) and morning surge group ( n =83).The biochemical indexes including blood lipids,24-hour average systolic blood pressure (24h SBP),24-hour mean diastolic blood pressure (24h DBP),daytime average systolic blood pressure ( dSBP ) , nighttime diastolic blood pressure ( dDBP ) , nocturnal mean systolic blood pressure (nSBP), nocturnal mean diastolic blood pressure (nDBP),blood pressure variability, blood pressure morning surge and NIHSS scores as well as BI scores were analyzed and compared among groups .Rseults There were significant differences in the levels of TG ,TC,LDL-C,HDL-C,ApoA,ApoB,Hcy,hs-CRP,24 h SBP,24 h DBP,dSBP,dDBP,nSBP,nDBP,24h SBPV, dSBPV, detection rate of blood pressure morning surge ,NIHSS scores,BI scores among normal IMT group ,IMT thickening group and IMT plaque group ( P <0.05).Conclusion The blood lipid,Hcy,hs-CRP,24 h SBPV,dSBPV,blood pressure morning surge in patients with cerebral infarction complicated by hypertension is correlated to atherosclerosis , which are independentrisk factors resulting in the pathogenesis and development of artherosclerosis .
Keywords：cerebral infarctionhypertensionblood pressure variabilityblood pressure morning summitatherosclerosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 508-510,515 )