The diagnostic value of conventional ultrasound and ultrasound elasticity imaging in diagnosis of breast solid nodule

LIU Liqin; SUN Xiang; TAN Jie

doi:10.3969/j.issn.1002-7386.2016.20.011

Abstract：Objective To evaluate the diagnostic value of conventional ultrasound and ultrasound elasticity imaging in diagnosis of benign or malignant breast solid nodules in order to provide an new method for early screening of breast cancer. Methods Eighty-four female patients with breast solid nodule ( 105 solid nodules ) who were admitted and treated in our hospital from May 2012 to October 2015 were enrolled in the study.All the patients received conventional ultrasound and ultrasound elasticity imaging examination.Taking the pathological diagnosis results after solid nodulectomy in onchocerciasis as gold standard, the accuracy, sensitivity, specificity, positive and negative predictive value in the diagnosis of breast solid nodule by means of conventional ultrasound scoring, ultrasound elasticity imaging scoring, strain rate ratio, conventional ultrasound combined with ultrasound elasticity imaging scoring were evaluated,moreover, the ROC curve was drawn by SPSS 20.0 software, finally,the results were statistically analyzed.Results The pathological examination results showed that among 105 solid nodules,there were 29 malignant nodules and 76 benign nodules.The accuracy, sensitivity, specificity, positive predictive value, negative predictive value by conventional ultrasound scoring, ultrasound elasticity imaging scoring,strain rate ratio, conventional ultrasound combined with ultrasound elasticity imaging scoring in diagnosis of benign or malignant breast solid nodules were ( 85.71%, 79.31%, 88.15%, 71.875%, 91.78%); ( 82.86%, 72.41%, 86.84%, 67.74%, 89.19%);(84.76%,75.86%,88.16%,70.97%,90.54%);(89.52%,93.10%,88.53%,71.05%,97.01%), respectively.The sensitivity by conventional ultrasound combined with ultrasound elasticity imaging scoring was significantly higher than that by conventional ultrasound scoring, ultrasound elasticity imaging scoring,strain rate ratio,respectively (χ2 =5.221,10.247,6.872, P <0.05).The area under ROC curve by conventional ultrasound scoring, conventional ultrasound combined with ultrasound elasticity imaging scoring,strain rate ratio, ultrasound elasticity imaging scoring was 0.835,0.867, 0.806,0.793,respectively.Conclusion The conventional ultrasound and ultrasound elasticity imaging have certain value in diagnosis of benign or malignant breast solid nodules, moreover, conventional ultrasound combined with ultrasound elasticity imaging scoring can increase the sensitivity and diagnostic efficiency in diagnosis of malignant breast nodule,which should be regarded as a measure of early screening of breast cancer in clinical practice.