Effects of two kinds of pulmonary lobectomy on perioperative clinical indexes, inflammatory reaction degree and postoperative complications of patients with non small cell lung cancer in stageⅠ~Ⅱ

doi:10.3969/j.issn.1002-7386.2016.18.006

Abstract：Objective To observe and compare the effects of traditional thoracotomy and complete video-assisted thoracoscopic surgery ( VATS) pulmonary lobectomy on perioperative clinical indexes, inflammatory reaction degree and postoperative complications of patients with non small cell lung cancer (NSCLC) in stage Ⅰ ~Ⅱ.Methods One hundred and forty patients with NSCLC in stage Ⅰ ~Ⅱ who were admitted and treated in our hospital from February 2011 to February 2015 were randomly divided into two groups: thoracotomy group ( n =70) and VATS group ( n =70).The patients in thoracotomy group were treated by traditional thoracotomy,however,the patients in VATS group were treated by complete VATS pulmonary lobectomy.The perioperative clinical indexes, VAS scoring after operation, CRP levels before and after operation and postoperative complications were observed and compared between two groups.Results The intraoperative hemorrhage volume, chest drainage time, out-of-bed activity time and length of staying in hospital in VATS group were superior to those in thoracotomy group( P <0.05).However there were no significant differences in operation time, group number of lymph node dissection between 2 groups( P <0.05).The VAS scores on 1d, 3d and 30d after operation in VATS group were significantly lower than those in thoracotomy group( P <0.05).The levels of CRP on 1d and 3d after operation in VATS group were significantly lower than those in thoracotomy group( P <0.05).The incidence of postoperative complications in VATS group was significantly lower than that in thoracotomy group ( P <0.05).Conclusion As compared with traditional thoracotomy pulmonary lobectomy, the complete VATS pulmonary lobectomy can decrease the injury degree of operation in patients with NSCLC in stage Ⅰ ~Ⅱ,and can promote rehabilitation of organism, relieve postoperative pain, alleviate inflammatory reaction degree,moreover,which is helpful to prevent occurrence of postoperative complications.