The preventive effects of povidone iodine rinsing combined with pranoprofen ophthalmic solution on infections and macular edema of patients after receiving cataract phacoemulsification

FU Chunyan; FU Xiaolin; CHEN Jianzhi

doi:10.3969/j.issn.1002-7386.2016.17.008

Abstract：Objective To observe the preventive effects of povidone iodine rinsing combined with pranoprofen ophthalmic solution on infections and macular edema of patients after receiving cataract phacoemulsification. Methods Eighty patients with cataract who were treated in our hospital were divided into observation group and control group according to random digits table. The patients in control group were treated by povidone iodine rinsing only, however, the patients in observation group were treated by povidone iodine rinsing combined with pranoprofen ophthalmic solution. The best corrected visual acuity, intraocular pressure, flare value of anterior chamber, the thickness of the anterior chamber, thickness of central fovea of macula,total scores of ocular signs and infection status were observed and compared between two groups before and after treatment,besides, the incidences of macular edema were observed after 3-month follow-up. Results After treatment, the best corrected visual acuity in observation group was superior to that in control group ( P <0. 05). The flare value of anterior chamber, thickness of the macular and total scores of ocular signs in observation group were significantly lower than those in control group ( P <0. 05). The incidence of infections in observation group was 5. 00%,which was significantly lower than that 25. 00% in control group ( P <0. 05). The incidence of macular edema in observation group on 1w,1m,3m after treatment, respectively,which was lower than that in control group,but there was no significant difference between two groups ( P >0. 05). Moreover the therapeutic effects in observation group were superior to those in control group. Conclusion The povidone iodine rinsing combined with pranoprofen ophthalmic solution can effectively prevent the occurrence of infection and macular edema after cataract phacoemulsification,which is beneficial to patient's prognosis,thus it is worth using widely in clinical practice.