Therapeutic effects of puerarin combined with telmisartan on obesity hypertension

doi:10.3969/j.issn.1002-7386.2016.14.015

Abstract：Objective To observe the therapeutic effects of puerarin combined with telmisartan on obesity hypertension .Methods A total of 160 patients with obesity hypertension who were admitted and treated in our hospital from June 2013 to June 2015 were randomly divided into observation group ( n =80) and control group ( n =80).The patients in control group were treated by telmisartan ,however,the patients in observation group ,on the basis of control group , were given puerarin,with a treatment course of one month.After treatment, therapeutic effects,the levels of high density lipoprotein cholesterol ( HDL-C ) , low density lipoprotein cholesterol ( LDL-C ) , trigalloyl glycerol ( TG ) , total cholesterol ( TC ) , systolic blood pressure ( SBP ) , diastolic blood pressure ( DBP ) , fasting plasma glucose ( FPG ) , glycosylated hemoglobin (HbA1C), body mass index (BMI),waist circumference, left ventricular diastolic thickness (PWT), microalbuminuria ( MAU) and adverse reactions were detected and compared between two groups .Results There were significant differences in the total effective rates between two groups ( P <0.05).As compared with those in control group ,the levels of TC,TG,SBP, DBP,FBG,HbA1C, BMI, waist circumference,PWT,MAU in observation group were significantly decreased ( P <0.05). However there were no significant differences in the levels HDL-C and LDL-C before and after treatment in both groups ( P >0.05).The cardiovascular adverse reactions were not observed in both groups .Conclusion The puerarin combined with telmisartan is effective in treating obesity hypertension ,which can obviously decrease the levels of blood lipid , blood pressure , blood sugar , the obesity related indexes and urine MAU of patients ,without obvious adverse reactions .