Comparative study on the change trend of leucocyte in patients with cerebral infarction in different sides of middle cerebral artery at acute phase

HU Ruhai; LIAO Xinyu; XIANG Ling

doi:10.3969/j.issn.1002-7386.2016.14.012

Abstract：Objective To explore the change trend of leucocyte in patients with cerebral infarction in different sides of middle cerebral artery at acute phase .Methods One hundred and five patients with acute middle cerebral artery infarction who were admitted and treated in our hospital from May 2013 to May 2014 were divided into left side group ( n =54 ) and right side group ( n =51 ) , according to different infarction position .The white blood cell count , neutrophils proportion , lymphocytes proportion in peripheral blood , incidence of pulmonary infection within 1 week after admission were detected and compared between two groups .Moreover the neurologic functional impairment scoring ( NIHSS) and degree of disability scale ( mRS) 1 months after admission were evaluated in both groups .Results There were no significant differences in the white blood cell count , neutrophils proportion , lymphocytes proportion in peripheral blood , incidence of pulmonary infection NIHSS and mRS between two groups ( P <0.05).After these patients were redivided into different groups according to whether the patients had pulmonary infection or not , there were no significant differences in the white blood cell count and neutrophils proportion in patients with middle pulmonary infection between two groups ( P <0.05).However there were significant differences in the white blood cell count and classification in patients without pulmonary infection at the first day of invasion between left side group and right side group ( P <0.05).The neutrophils proportion in patients without pulmonary infection of left side group reached peak at the first day of invasion ,then,which was gradually decreased to normal levels within 1 week, however , which in right side group was transiently increased at the third day of invasion .The lymphocytes proportion in patients without pulmonary infection of left side group was decreased to the lowest levels at the first day of invasion , which was gradually increased to normal levels within 1 week,however, which in right side group was transiently decreased at the third day of invasion( P <0.05).Conclusion The change trend of the leucocytes in non -pulmonary infectious patients with acute middle cerebral artery infarction at different sides is quite different , which suggests that the immunosuppressive mechanism caused by acute middle cerebral artery infarction at different sides may be different to some extent .