Effects of whole thor ascopic surgery and open chest surgery on early indexes of trauma and immune function in patients with non small cell lung c ancer
Abstract：Objective To investigate the effects of whole thorascopic surgery and open chest surgery on early indexes of trauma and immune function in patients with non small cell lung cancer ( NSCLC ) .Methods Fifty-six patients with NSCLC who underwent surgical treatment in our hospital from June 2012 to August 2015 were divided into two groups according to different surgical modes .The 28 patients who received posterolateral thoracotomy were served as observation group,and the other 28 patients who received whole thorascopic surgery were served as control group .The therapeutic effects including intraoperative bleeding volume , intraoperative blood transfusion volume ,operation time and hospitalization time were observed ,moreover, the changes of inflammatory factors levels and immune cells levels before and after treatment were detected and compared between two groups .Re sults The intraoperative bleeding volume , intraoperative blood transfusion volume , operation time and hospitalization time in observation group were superior to those in control group ( P <0.05 ) .After treatment the levels IL-6, IL-2R,CRP,SAA in observation group were significantly lower than those in control group ( P <0.05).The immune function indexes including CD 4+,CD8+,CD4+/CD8+in observation group were superior to those in control group ( P <0 .05 ) .Conclusion The whole thorascopic surgery has better therapeutic effects on NSCLC at early period , which can improve patient ’ s immune function ,thus it is worth spreading application in clinic .
Keywords：non small cell lung cancerwhole thoracoscopeopen chest surgery from rear lateral regionimmune function
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1943-1945 )