Analysis for pathogenesis characteristics of intracranial tumor

WANG Jianing; GENG Zuojun

doi:10.3969/j.issn.1002-7386.2016.04.007

Abstract：Objective To investigate the pathogenesis regulation of intracranial tumors in order to enhance the accuracy of preoperative diagnosis. Methods The data including patient’s age,sex and histopathological types in 1,179 patients with intracranial tumor were retrospectively analyzed. According to the classification criteria of central nervous system tumors by WHO in 2007,the statistical results were compared with those reported in literatures to explore pathogenesis regularity of intracranial tumors. Results The age of patients with high incidence of intracranial tumor was peaked at 40 ~ 60 years,with females being slightly more than males. The histopathological types of the tumor were meningiomas(30. 28℅), neurocytoma(29. 7℅),pituitary adenoma(20. 78℅),neurinoma(10. 77℅),metastatic tumor(2. 97℅),craniopharyngioma (2.37℅),lymphomas(1.44℅),chordoma(0.76℅),germ cell tumor(0.68℅)and the other tumors(0.25℅). The incidence of neurocytoma was slightly less than that of meningiomas,however,according to former reports,the former was higher than the latter. The frequent histopathological types in children patients were astrocytic tumors(30℅),ependymoma(13.33℅),craniopharyngioma (13.33℅)and medulloblastoma(8.33℅). The frequent histopathological types in elderly patients were meningioma(31. 78℅), astrocytic tumors(22.03℅),pituitary tumor(14. 83℅)and neurinoma(10. 17℅). Conclusion There is a certain regularity in sex and age of patients as well as histopathological types of intracranial tumors. With the development of imaging techniques,the incidence rate of intracranial tumor is increased in recent years.