The influencing factors on prognosis of squamous carcinoma of the cervix
XIN Huadong
Abstract：Objective To study retrospectively clinicopathological characteristics of patients with squamous carcinoma of the cervix and the effects of cyclooxygenase-2 (COX-2) on patients’ prognosis.Methods The clinical data about 77 cases of primary squamous carcinoma of cervix were collected and analyzed,moreover, the expression levels of COX-2 protein were detected by immunohistochemistry ( SP) to explore the influencing factors on prognosis of squamous carcinoma of the cervix. Results The 5-year overall survival rate was 74.03%(57/77) .The survival analysis showed that histological grades,clinical staging,lymph node metastasis,latero-uterus infiltration, vessel tumor embolus, muscular-invasive depth and COX-2 affected significantly the prognosis of patients with squamous carcinoma of the cervix ( P <0.05).Conclusion The histological grades,clinical staging,lymph node metastasis,latero-uterus infiltration, vessel tumor embolus, muscular-invasive depth and COX-2 are independent prognostic factors of squamous carcinoma of the cervix.
Keywords：squamous carcinoma of the cervixCOX-2prognosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 3698-3702 )