Effects of different analgesia modes after cesarean section on neonatal neurobehavioral scores and adaptive capacity scores

doi:10.3969/j.issn.1002-7386.2015.23.004

Abstract：Objective To observe the effects of different analgesia modes after cesarean section on neonatal neurobehavioral scores and adaptive capacity scores ( NACS).Methods One hundred and twenty-eight parturients after cesarean section with continuous epidural anesthesia who admitted into our hospital from August 2013 to October 2014 were enrolled in the study.These parturients were randomly divided into 4 groups according to different analgesia modes after cesarean section,with 32 parturients in each group.The first three groups were observation groups and the last group was control group.The parturients in group 1 received epidural analgesia with 0.2%ropivacaine mesylate,and group 2 with 0.2%ropivacaine mesylate plus 3μg/h fentanyl, group 3 with 0.2% ropivacaine mesylate plus 80μg/h morphine, however, the parturients in group 4 received intramuscular injection with pethidine hydrochloride only during pain.The visual analog scales (VAS) were recorded on 2h,6h,24h,48h after operation,moreover, Apgar scores on 1min and 5 min after operation and NACS on 20h after operation were observed and recorded for the 4 groups.Results The VAS scores on 24h and 48h after operation in group 1 were significantly higher than those in group 2 and group 3 ( P <0.05).The VAS scores in control group in different time points after operation were significantly higher than those in group 2 and group 3 ( P <0.05 ) , moreover, the VAS scores in control group on 2h and 6h after operation were significantly higher than those in group 1( P <0.05).There were no significant differences in Apgar scores on 1min and 5 min after operation and NACS on 20h after operation among 4 groups ( P >0.05).Conclusion Ropivacaine mesylate combined with fentanyl or morphine has obvious analgesia effects on parturients after cesarean section, moreover, which has no adverse effects on neonatal neurobehavioral scores and adaptive capacity scores.