Analysis for partial RhD genotype
Abstract:Objective To investigate genotyping of 7 cases of partial RhD specimens .Methods The genetyping technique ( PCR-SSP ) was performed for partial RhD variants identified by common serological tests .Results Among 30 specimens identified as D variants during routine serological experiment ,7 specimens were defined as partial RhD and 23 specimens as weak D .Then 7 specimens of partial RhD were genetyped further in which 4 cases were D Cat .ⅥⅢ,1 case was D Cat.Ⅵ type 2,1cases was D Cat.Ⅵ type 1 and 1 case was RHD-CE(2-9)-D.Conclusion The routine serological experiments can not differentiate partial D from weak D ,however ,the molecular biological methods can type accurately in order to ensure the safety of blood transfusion .
Keywords:Rh negativepartial RhDweak Dgenotype
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 179-181 )
