The application of contrast-enhanced ultrasound in the diagnosis of lower extremity arterial disease
Abstract：Objective To explore the application value of contrast-enhanced ultrasound ( CEUS ) in the diagnosis of lower extremity arterial disease ( LEAD) .Met hods Ultrasound contrast agent was injected into peripheral vein of 80 healthy subjects and 80 patients with LEAD .The condition of blood flow perfusion in calf muscle was detected by contrast-enhanced ultrasound.Time intensity curve (TIC) was analyzed by mathematical model to get the time to peak intensity (TTP).Results TIC revealed TTP in patients with LEAD was 84s(39~142s)at rest period,which was 38s(19~65s in control group,there was a significant difference between LEAD group and control group ( P <0.01).After leg exercise test,TTP in control group was 11s(9~22s),however,which was 52s(27 ~105s) in LEAD group,there was a significant difference between LEAD group and control group ( P <0.01).After age adjustment there was a significant difference between LEAD group and control group ( P <0.01).However TTP was not correlated to patient's age and ankle brachium index .Conclusion CEUS is an novel diagnostic method for evaluating perfusion disorder of skeletal muscles .
Keywords：ultrasound contrastlower extremity arterial diseaseskeletal muscleperfusion
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 978-981 )