Study on the magnetic resonanec diffusion tensor imaging parameters oft he nucleus pulposus of degenerated intervertebral disks according to Pfirrmann grading
Abstract：Objective To quantitatively analyze the changes of magnetic resonance diffusion tensor imaging parameters of degenerated intervertebral disks according to Pfirrmann grading .Methods 72 patients and 30 healthy volunteers were examined by 3.0T MRI for T1,T2 and DTI scan.According to T2WI of disks,the normal and degenerated intervertebral disks were divided into five groups ,and the correlation among relative T2 values,ADC values and FA values in the five groups was analyzed .Results The relative T2 values in 1,4 and 5 grade intervertebral disk were positively correlated with those of ADC ( P <0.05),however,which were negatively related to those of FA (P <0.05).The relative T2 values in grade 2 intervertebral disk were positively correlated to those of ADC ( r =0.4941, P <0.01),however,which were not related with those of FA ( r =-0.2998, P>0.05).The relative T2 values in grade 3 intervertebral disk were not correlated with those of ADC ,FA ( P >0.05).However the parameters value according to Pfirrmann grading was related to that of relative T 2,FA,ADC (P <0.01).There were significant differences in relative T 2 values,FA,ADC between grade 1 intervertebral disk and the other grade intervertebral disks ( P <0 .05 ) .Conclusion DTI can be regarded as a useful indicator to evaluate intervertebral disk function .The degeneration process of slight and moderate degree degenerated disks may be reversed through treatment .
Keywords：magnetic resonancediffusion tensorintervertebral diskdegeneration
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 3369-3371 )