Study on Anti-Coagulant Activity of Sulfated Nsotoc Sphaeroides Kützing Polysaccharide
ZHU Yuting
YUAN Jie
YANG Jie
TIAN Rui
ZENG Zhi
MO Kaiju
Abstract：This paper investigated the anticoagulant activity of Nostoc Sphaeroides Kützing polysaccha-ride’ s sulfuric acid ester,whose substitution degrees were 0,0.51,1.01 respectively.The results showed:Nostoc Sphaeroides Kützing polysaccharide’ s sulfuric acid ester could obviously prolong APTT and TT, and depended on the concentration but did not play a significant role to PT.So the results mainly illustra-ted that it played the function of anticlotting through inhibiting endogenous blood coagulation process and conjunct blood coagulation way,but it showed weak effect on exogenous blood coagulation way.
Keywords：Nostoc Sphaeroides Kützingpolysaccharidesulfamide acidanticoagulant activity
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 368-370,379 )