Clinical observation of self-designed jianpi bushen huayu decoction in treating post-stroke qi deficiency constipation
Tian Guojie
Feng Mingxiang
Wang Dagang
Wang Ya
Liao Mingjuan
Cai Fei
Huang Yi
Abstract：Objective To investigate the clinical efficacy of a self-made Jianpi Bushen Huayu Decoction(a formula for invigorat-ing the spleen,tonifying the kidneys,and resolving blood stasis)in treating post-stroke Qi deficiency constipation,providing references for clinical practice.Methods Seventy-nine patients with post-stroke constipation admitted to the Department of Re-habilitation at Chinese Medicine Hospital of Qijiang District Chongqing from January 2022 to December 2023 were enrolled and randomly assigned to an observation group(n=39)and a control group(n=40)using the random number table method.Both groups received basic treatment.The control group was orally administered polyethylene glycol 4000 powder,while the obser-vation group received the self-made Jianpi Bushen Huayu Decoction.Treatment lasted 28 days.Assessments conducted 3 days before treatment and 3 days after the treatment ends:Traditional Chinese Medicine(TCM)syndrome scores,constipation symptom severity,Patient Assessment of Constipation Quality of Life Questionnaire(PAC-QOL)questionnaire scores,and residual colonic marker quantity.Results No significant difference in TCM syndrome scores was observed between the two groups before treatment(P＞0.05).After treatment,both groups showed reduced scores,with the observation group scoring significantly lower than the control group(P＜0.05).No significant difference in constipation symptom severity was noted pre-treatment(P＞0.05).Post-treatment,both groups improved significantly,with the observation group outperforming the control group(P＜0.05).Pre-treatment scores showed no significant difference in PAC-QOL scores(P＞0.05).Post-treat-ment,both groups had lower scores,with the observation group scoring significantly lower than the control group(P＜0.05).No significant difference in residual colonic markers was found pre-treatment(P＞0.05).Post-treatment,both groups showed reduced residual markers,with the observation group having significantly fewer than the control group(P＜0.05).Conclusion The Jianpi Bushen Huayu Decoction markedly improves intestinal motility,alleviates TCM syndromes and constipation symp-toms,and raises quality of life in patients with post-stroke Qi deficiency constipation.Its clinical efficacy is robust,warranting broader clinical application.
Keywords：Self-made jianpi bushen huayu decoctionStrokeConstipation
Publication Date：2025-02-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 124-128 )