Intravoxel incoherent motion imaging for the diagnostic value of renal benign and malignant tumors:a meta-analysis
Yang Xue
Zhang Xueqin
Zheng Huanlu
Hu Meihong
Gan Liwei
Li Junfan
Luo Yindeng
Abstract：Objective To analyze the accuracy of parameters such as true diffusion coefficient(D),pseudo-diffusion coeffi-cient(D*),and perfusion fraction(f)from intravoxel incoherent motion(IVIM)imaging for the diagnosis of benign and malignant renal tumors,aiming to provide support for clinical interventions.Methods A literature search was conducted in English databases including Web of Science,PubMed,and Chinese databases including CNKI,VIP,and Wanfang Data for literature related to the diagnosis of renal benign and malignant tumors using IVIM parameters,up to March 2024.Relevant data from the included literature were summarized and statistically analyzed using Metadisc 1.4 and STATA 15.1 software.Results A total of 9 articles(5 in Chinese and 4 in English)were included in this study,involving 865 renal tumor lesions.The pooled sensitivity of IVIM parameters D,D*,and f for the diagnosis of renal benign and malignant tumors was 0.85[95％CI(0.73-0.92)],0.83[9 5％CI(0.75-0.88)],and 0.68[95％CI(0.58-0.77)],respectively.The pooled spe-cificity was 0.92[95％CI(0.84-0.96)],0.63[95％CI(0.52-0.73)],and 0.77[95％CI(0.31-0.96)],respective-ly.The areas under the summary receiver operating characteristic(SROC)curve were 0.95,0.78,and 0.73,respectively.Conclusion The IVIM parameter D indicates a high diagnostic value for distinguishing between benign and malignant renal tumors,while parameters D*and f demonstrate moderate diagnostic value.
Keywords：Renal tumorsMagnetic resonance imagingIntravoxel incoherent motiondifferential diagnosisMeta-analysis
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 51-58 )