Predictive efficacy of the peripheral blood platelet-to-lymphocyte ratio(PLR)for postoperative infection in the urinary system
Fan Jie
Zhang Wuhe
Ding Xia
Jiang Yao
Guo Wei
Liu Xiaona
Abstract：Objective To explore the predictive efficacy of the peripheral blood platelet-to-lymphocyte ratio(PLR)for post-operative infection in patients receiving surgery in the urinary system,aiming to provide a reference for clinical decision-mak-ing.Methods A total of 122 patients who underwent urinary system surgery at the Xijing 986 Hospital from October 2020 to October 2023 were selected as the study participants and divided into an infection group(n=48)and a non-infection group(n=74)based on whether postoperative infection occurred.All patients underwent peripheral blood platelet and lymphocyte testing with a fully automated blood analyzer on the day before surgery,and the PLR was calculated.The receiver operating characteristic(ROC)curve analysis was used to assess the predictive value of PLR for postoperative infection in patients re-ceiving urinary system surgery.Multifactorial logistic regression analysis was employed to explore the influencing factors of postoperative infection in patients.Results Patients in the infection group had significantly higher peripheral blood platelet counts and PLR than those in the non-infection group,and significantly lower lymphocyte counts than those in the non-infec-tion group(P＜0.05).The area under the ROC curve(AUC)for platelets and lymphocytes in predicting postoperative in-fection in patients was 0.709(95％CI:0.664-0.759)and 0.826(95％CI:0.781-0.876),respectively.Moreover,the AUC for PLR in predicting postoperative infection in patients was 0.932(95％CI:0.887-0.982).No statistically signifi-cant differences were noted in gender,age,body mass index,disease type,24-hour urine volume,proportion of patients re-ceiving prophylactic antibiotics,postoperative systolic blood pressure,and postoperative diastolic blood pressure between the non-infected and infected groups(P＞0.05);however,statistically significant differences were found in the duration of in-dwelling catheter postoperatively,the number of invasive diagnostic and therapeutic procedures,surgical methods,white blood cell count,C-reactive protein(CRP),time of operation,and hospital stay between the two groups(P＜0.05).Multi-variate logistic stepwise regression analysis showed that the duration of the indwelling catheter postoperatively(OR=2.421,95％CI:1.412-4.150),surgical method(OR=1.808,95％CI:1.191-2.744),time of operation(OR=1.891,95％CI:1.233-2.899),length of hospital stay(OR=2.751,95％CI:1.513-5.002),white blood cell count(OR=2.140,95％CI:1.316-3.480),CRP(OR=2.502,95％CI:1.491-4.197),and PLR(OR=3.168,95％CI:1.808-5.549)were influencing factors for postoperative infection in patients(P＜0.05).Conclusion A high preoperative PLR remains one of the risk factors for postoperative infection in patients receiving surgery in the urinary system and has the potential to be an important indicator for predicting postoperative infection in the urinary system.
Keywords：Platelet-to-lymphocyte ratioUrinary systemPostoperative infectionPredictive efficacy
Publication Date：2024-07-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 90-95 )