Analysis of risk factors for systemic inflammatory response syndrome in patients with benign prostatic hyperplasia after transurethral plasmakinetic resection of the prostate

Wang Shuheng; Li Jiuzhi; Gao Yang; Liu Bide; Lei Peng

doi:10.11986/j.issn.1673-873X.2024.07.13

Abstract：Objective To explore the risk factors for systemic inflammatory response syndrome(SIRS)after transurethral plasmakinetic resection of the prostate(TUPKRP)in patients with benign prostatic hyperplasia(BPH),in order to provide a reference for clinical decision-making.Methods Clinical data of 170 BPH patients who underwent TUPKRP surgery at a hospital in Xinjiang from May 2019 to May 2022 were collected.Patients who developed postoperative SIRS were included in the SIRS group,and those who did not were included in the non-SIRS group.General information,laboratory test results,and perioperative indicators of the two groups of patients were collected.Univariate analysis and multivariate logistic regres-sion model were used to analyze the risk factors for SIRS after TUPKRP.Results Among the 170 BPH patients treated with TUPKRP,32 cases(18.82％)developed postoperative SIRS.There were statistically significant differences in age,presence or absence of combined type 2 diabetes mellitus(T2DM),preoperative prostate volume,presence or absence of preoperative urinary tract infection,preoperative serum albumin(Alb)level,preoperative hemoglobin(Hb)level,and op-eration time between the SIRS group and the non-SIRS group(P＜0.05);whereas there were no statistically significant differences in body mass index,history of hypertension,preoperative International Prostatic Symptom Score(IPSS),preop-erative white blood cell(WBC)count,intraoperative blood loss,and postoperative catheter retention time between the two groups(P＞0.05).The logistic regression model analysis indicated that advanced age(OR=1.194,95％CI:1.078-1.322),presence of combined T2DM(OR=3.142,95％CI:1.412-6.991),and large preoperative prostate volume(OR=1.087,95％CI:1.029-1.148)are independent risk factors for the occurrence of SIRS after TUPKRP(P＜0.05),while high preoperative Hb level(OR=0.903,95％CI:0.838-0.973)is an independent protective factor for the occur-rence of SIRS after TUPKRP(P＜0.05).Conclusion The incidence of SIRS after TUPKRP remains high.Advanced age,combined T2DM,and large preoperative prostate volume are independent risk factors for the occurrence of SIRS after TUP-KRP,while high preoperative Hb level is an independent protective factor.Targeted interventions can be made based on the above-mentioned factors to reduce the occurrence of postoperative SIRS.