Analysis of the correlation between TCM constitution and circadian blood pressure rhythms in college students

Gong Yue; Tang Mingjie; Zhang Caisheng; Zhang Jixin; Li Shengnan; Quan Hongjiao; Tao Chengyao; Deng Ying

doi:10.11986/j.issn.1673-873X.2024.05.09

Abstract：Objective This study aimed to investigate the distribution characteristics of Traditional Chinese Medicine(TCM)constitutions among college students in Changsha and explore the correlation between TCM constitution and circadian blood pressure rhythms.Methods A convenience sampling was conducted between October 2023 and April 2024 at a university in Changsha,involving 437 students who underwent questionnaire surveys,physical examinations,and ambulatory blood pres-sure monitoring.TCM constitutions were determined using the TCM Constitution Survey Scale,and correlations between TCM constitution,ambulatory blood pressure,and circadian blood pressure rhythms were analyzed using Pearson correla-tion,Spearman correlation,and binary logistic regression.Results There were statistically significant differences in body mass index(BMI),24-hour systolic blood pressure(SBP),and daytime SBP among participants with different TCM consti-tutions(P＜0.05).Among them,13 had normal high values of 24-hour SBP,and 13 had abnormal values,accounting for 5.9％of the total respondents;20 had normal high values of 24-hour diastolic blood pressure(DBP),and 7 had abnormal values,accounting for 6.2％of the total respondents;183 had non-dipping SBP diurnal rhythm,accounting for 41.9％of the total respondents;88 had non-dipper type DBP diurnal rhythm,accounting for 20.1％of the total respondents.Among the participants,125 were of a normal constitution(28.6％),and 312 were of a biased constitution(71.4％).Correlation analysis showed that some TCM constitution scores(such as yang-deficiency,blood stasis constitution,and qi-deficiency constitution)were significantly correlated with some dynamic blood pressure indicators(24-hour SBP,daytime SBP,night-time SBP;P＜0.05),but the correlations were all weak.Binary logistic regression analysis results showed that compared with the normal constitution,yang-deficiency constitution is a risk factor for the occurrence of non-dipper type SBP(OR=1.977,95％CI:1.083-3.610,P=0.027),and yin-deficiency constitution is a protective factor for the occurrence of non-dipper type DBP(OR=0.350,95％CI:0.135-0.950,P=0.030).Conclusion The abnormal situation of blood pressure diurnal rhythm among college students in a university in Changsha city is quite serious;compared with the normal constitu-tion,yang-deficiency constitution is a risk factor for abnormal SBP diurnal rhythm,and yin-deficiency constitution is a pro-tective factor for abnormal DBP diurnal rhythm.