Impact of different examination sequences of CT enterography and colonoscopy on adverse reactions to iodinated contrast media
WU Xin
TANG Hui
YAO Xi
WANG Qin
XIAO Shuping
CHEN Dongping
Abstract：Objective To investigate the impact of examination sequence of CT enterography(CTE)and colonoscopy on the incidence of adverse reactions to iodinated contrast media in patients with suspected inflammatory bowel disease(IBD).Methods A total of 485 patients with suspected IBD were prospectively enrolled and randomly assigned,using a random number table,into two groups:Group A(265 cases)underwent colonoscopy followed by CTE,while Group B(220 cases)underwent CTE prior to colonoscopy.The incidence of iodinated contrast media-related adverse reactions was compared between the two groups using the Chi-square test.Results In Group A,a total of 39 patients(14.7％)experienced contrast-related adverse reactions,including 34 cases(12.8％)with mild reactions and 5 cases(1.9％)with moderate reactions.In Group B,two patients(0.9％)experienced only mild adverse reactions.The overall incidence of adverse reactions was significantly higher in Group A than in Group B(x2=36.82,P＜0.001).Conclusion In patients suspected of IBD,performing CTE before colonoscopy can significantly reduce the risk of adverse reactions to iodinated contrast media.
Keywords：Inflammatory bowel diseaseCT enterographyColonoscopyIodinated contrast agentAdverse reaction
Publication Date：2025-11-15
Online Publishing Date：2025-12-15(First online date of this platform, not the publication date of the document)
Pages：5( 723-727 )