Mixed neuroendocrine-non-neuroendocrine neoplasm of the gallbladder with liver metastasis:a case report
Abstract：Case: A 61-year-old female patient was admitted to the hospital due to abdominal pain for more than 7 years. The pain was persistent and radiated to the shoulder and back. Since the onset of the disease, the patient's mental state and appetite were generally normal, with normal bowel and urine function. In the past year, her body weight decreased by about 4 kg. She had a history of hepatitis B for more than 10 years, without a family history of tumors, trauma, or genetic diseases. Laboratory tests: increased globulin (37.2 g/L), significantly elevated glutamyl transferase (135 U/L), and reduced albumin-globulin ratio (1.23). Tumor markers: increased neuron-specific enolase (17.68 ng/mL). Abdominal ultrasound and contrast-enhanced ultrasound: a solid nodule in the gallbladder, approximately 3.7 cm × 2.7 cm in size, with unclear boundaries from the gallbladder wall. It showed high enhancement during the arterial phase, began to fade during the portal venous phase, and showed low enhancement during the delayed phase; multiple hypoechoic nodules in the liver, the largest located in the right posterior lobe, approximately 1.2 cm × 1.1 cm in size, with unclear boundaries, showing ring-like progressive high enhancement during the arterial phase, began to fade during the portal venous phase, and showed low enhancement during the delayed phase (Figure 1).
Keywords：Gallbladder NeoplasmsHepatic MetastasisMagnetic Resonance ImagingTomographyX-Ray Computed
Publication Date：2025-09-15
Online Publishing Date：2025-10-13(First online date of this platform, not the publication date of the document)
Pages：3( 608-610 )