Research progress of multimodal MRI in radiation-induced brain injury in nasopharyngeal carcinoma
LYU Wang
ZHOU Xiaoyu
ZHANG Jiuquan
LIU Daihong
Abstract：Radiation-induced brain injury(RIBI)is a common complication following radiotherapy for nasopharyngeal carcinoma,often leading to cognitive impairment and other neurological sequelae.Multimodal MRI,including perfusion-weighted imaging(PWI),susceptibility-weighted imaging(SWI),blood oxygen level dependent-functional MRI(BOLD-fMRI),diffusion MRI,voxel-based morphometry(VBM),and magnetic resonance spectroscopy(MRS),provides multidimensional insights into the pathophysiological mechanisms of RIBI by revealing vascular damage,neural dysfunction,structural injury,and metabolic abnormalities.Artificial intelligence techniques can further integrate multimodal MRI data to enable early prediction and individualized assessment of RIBI.This review summarizes recent advances in the application of multimodal MRI in RIBI associated with nasopharyngeal carcinoma.
Keywords：Nasopharyngeal carcinomaRadiation-induced brain injuryMagnetic resonance imaging
Publication Date：2025-09-15
Online Publishing Date：2025-10-13(First online date of this platform, not the publication date of the document)
Pages：6( 567-572 )