Research progress on cardiac MR evaluation of myocardial fibrosis in heart failure with preserved ejection fraction
CHEN Siwen
MA Yunting
ZHAO Xiaoying
ZHAO Xinxiang
Abstract：Heart failure with preserved ejection fraction(HFpEF)is a condition characterized by high heterogeneity and complex etiologies.Among its various underlying mechanisms,myocardial fibrosis is a key pathophysiological factor contributing to cardiac dysfunction in HFpEF patients.This article reviews the progress in applying various cardiac magnetic resonance(CMR)techniques,including delayed gadolinium enhancement(LGE),T1 mapping,extracellular volume(ECV),and CMR feature tracking(CMR-FT),to assess myocardial fibrosis in HFpEF.It highlights the role of these techniques in evaluating the distribution and severity of myocardial fibrosis,as well as their utility in risk stratification and prognostic assessment.Additionally,the article explores the future potential of artificial intelligence in enhancing CMR-based evaluations.
Keywords：Heart failureEjection fractionDiastolic heart failureMyocardial fibrosisMagnetic resonance imaging
Publication Date：2025-01-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 74-80 )