The value of logistic regression model based on CT and MRI features in distinguishing multilocular hepatic cysts from hepatic mucinous cystic tumors

LIU Hongjie; LI Yongyuan; ZHENG Jiaming; WEI Kai; YE Lu; LI Yanbo; CUI Jianmin; SUN Haoran

doi:10.19300/j.2024.L21742

Abstract：Objective To establish a logistic regression model based on CT and MRI features of multilocular hepatic cysts and mucinous cystic tumors(MCN),and analyze its value in differential diagnosis between the two entities.Methods A retrospective analysis was conducted on CT and MRI data from 65 cases of multilocular hepatic cystic lesions,including 13 males and 52 females.According to surgical pathology results,the cases were divided into hepatic cyst lesions(39 cases)and hepatic MCN lesions(26 cases).Chi-square tests were used to compare imaging findings between the two groups.Statistically significant CT and MRI features were further analyzed using multivariate logistic regression to construct a binary logistic regression model.The predictive performance of the model was evaluated using the receiver operating characteristic(ROC)curve,and the area under the curve(AUC),sensitivity,specificity,and accuracy were calculated.Results Significant differences were observed between hepatic cysts and hepatic MCNs in terms of the number of hepatic cystic lesions,the appearance of cyst wall and septa,nodular protrusions of cyst wall or septa,the thickness of solid components greater than 10 mm,types of septa,septa location,and the relationship between septa and cyst walls between hepatic cysts and hepatic MCNs(all P<0.05).Multivariate logistic regression analysis identified that septal type,and the relationship between septa and cyst walls as independent predictive factors(P<0.05).A logistic regression model constructed using these two factors achieved higher diagnostic performance(AUC=0.871)compared to using septal type(AUC=0.699)or the relationship between septa and cyst walls(AUC=0.795)alone.Conclusion A logistic regression model incorporating septal type,and the relationship between septa and cyst walls can effectively distinguish multilocular hepatic cysts from hepatic MCN,improving the preoperative imaging diagnostic accuracy for these lesions.