Retroperitoneal diffuse neurofibroma with predominantly fatty components:a case report and literature review
WANG Yiling
ZHANG Xiulan
HUANG Jinbai
Abstract：Objective To investigate the imaging features and pathological findings of retroperitoneal diffuse neurofibroma(DNF).Methods The imaging manifestations of a patient with huge retroperitoneal DNF,confirmed by surgical pathology,were retrospectively analyzed.Additionally,relevant literature was reviewed.Results CT and MRI revealed a giant,isolated retroperitoneal mass that predominantly consisted of fatty components with unclear boundaries.Multiple,scattered masses were seen within the solid component,which compressed and encapsulated the post-peritoneal vessels.The solid component showed mild enhancement on enhanced MRI and mild hypermetabolic activity on PET.Immunohistochemical analysis showed positive expression of S-100 and SOX-10.Conclusion DNF can occur in the retroperitoneum,and its clinical and imaging findings are not particularly specific.Diagnosis requires histopathological examination.
Keywords：Diffuse neurofibromaRetroperitoneumPositron emission tomographyMagnetic resonance imagingTomographyX-ray computed
Publication Date：2024-05-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 363-366 )