Advances in amide proton transfer imaging in prostate cancer
FANG Hongkun
HOU Weishu
LI Xiaohu
YU Yongqiang
Abstract：Amide proton transfer(APT)imaging is an imaging technique that can detect the saturation of amide protons to hydrogen proton exchange in free water,and can estimate the malignancy and invasiveness of tumors by detecting protein and peptide levels in cells.A review is presented on the research progress of APT imaging and its combination of T2 mapping,diffusion weighted imaging(DWI),intravoxel incoherent motion(IVIM)imaging,mDIXON-Quant sequence,and prostate-specific antigen(PSA)in prostate cancer diagnosis,risk stratification,and bone metastasis prediction.
Keywords：Amide proton transferProstate cancerGleason scoreProstate specific antigenMagnetic resonance imaging
Publication Date：2024-01-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 92-96 )