The application and research of MRI in the evaluation of treatment response to neoadjuvant chemoradiotherapy in rectal cancer
YANG Lanqing
WU Bing
Abstract：Neoadjuvant chemoradiotherapy (NCRT) following with total mesorectal excision has become the standard of care for the local advanced cancer at low or middle rectum. Some patients can even achieve a pathological complete re-sponse after NCRT, associating with an improved local control and survival rate, and increased probability of anus reserva-tion. Therefore it's important to precisely predict the probable response degree of tumor, and to evaluate the regression state after NCRT for making the best multidisciplinary and personalized therapeutic regime in clinical. In this paper, we reviewed the clinical values of MRI morphological parameters, including the situation of preoperative circumferential resection margin and the change of the tumor volume, and the functional parameters, including the dynamic contrast enhanced MRI and diffu-sion weighted imaging parameters.
Keywords：Rectal cancerMagnetic resonance imagingNeoadjuvant therapyTumor response
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 54-58 )