Progress of the quantitative susceptibility mapping (QSM) in measuring the brain iron accumulation during the normal brain aging
PANG Bingxin
GENG Zuojun
Abstract：The quantitative susceptibility mapping (QSM) algorithms have the advantages of less vulnerable to image artifacts and clear delineation of tissue boundaries, and can quantitatively analyze the magnetic susceptibility values of para-magnetic materials. Using QSM algorithms to measure the magnetic susceptibility values of different brain tissues, analyze the correlation between iron accumulation in brain nucleis and age, we found that the decline in brain output, motor and cognitive functions may be related to changes in brain iron accumulation during the normal brain aging, which is significantly meaning-ful to predict the brain functional decline in the normal aging. In this article, we reviewed the principle of QSM in measuring brain iron accumulation and the correlation between brain iron accumulation in different brain tissues and age.
Keywords：Brain iron accumulationNormal brain agingQuantitative susceptibility mappingBrain nucleiMagnetic susceptibility
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 32-34 )