The research advances in MR imaging of multiple sclerosis
RUI Wenting
YAO Zhenwei
Abstract：Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by multifocal demyelinating lesions mainly in white matters of central nervous system and repeated attack with alternated remission and relapsing. Clini-cal manifestations of MS are quite unspecific and conventional MRI has its limitation in diagnosis of MS. While, many new MRI techniques may help to detect minor/cortical lesions, inflammation of leptomeninges, and even changes of normal-ap-pearing brain parenchyma, which may contribute significantly in revealing changes of different pathological features during disease courses, predicting neuro-functions and behavioral changes. This paper summarizes the progresses in application of double inversion-recovery (DIR) imaging, phase difference-enhanced imaging (PADRE), contrast enhanced fluid-attenuated inversion recovery (CE-FLAIR) imaging, magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), and func-tional MRI techniques in MS.
Keywords：Multiple sclerosisMagnetic resonance imagingCortical lesionInflammatory reactionNeuro-function
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 27-31 )