Advances in application of intravoxel incoherent motion diffusion weighted imaging in breast cancer
WU Peiqi
LIU Zaiyi
LIANG Yanli
CHENG Leishu
Abstract：Intravoxel incoherent motion DWI (IVIM-DWI) is a new DWI technique,which uses the IVIM double exponential model to obtain parameters,such as the pure diffusion coefficient,the pseudo-diffusion coefficient,and the perfusion fraction,etc.Thus,IVIM-DWI can be used to non-invasively quantify the pure diffusion of water molecules and microcirculation perfusion of body tissue separately in vivo,and it has obvious advantages compared with the traditional DWI.IVIM-DWI has been gradually apphed to clinical practice,and it has become one of the hot spots in breast cancer research.This paper describes the basic principle of IVIM-DWI and its related parameters,then discusses the effect of b-value selection on the relevant parameters.The progress of this technique in breast cancer (malignant identification,molecular typing,prognostic factors and efficacy evaluation,etc.) and the challenges are reviewed.
Keywords：Breast cancerDiffusion weighted imagingIntravoxel incoherent motionDiagnosisMolecular subtypePrognostic factorNeoadjuvant chemotherapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 690-694 )