Solitary bone plasmacytoma in thoracic vertebrae:case report and literature review
LIU Chunming
XU Liang
Abstract：Objective To illustrate the clinical manifestations, image features, and differential of solitary bone plasmacytoma (SBP)in thoracic vertebrae. Methods CT and MRI images of a case with SBP in thoracic vertebrae were analyzed, and literatures were reviewed. Results Precontrast CT scan revealed moderately anterior wedging and osteolytic bone destruction at T10 vertebral body. The focus was homogeneous with residual bone crest located on the edge, without typical "mini brain" sign, calcification and tumor bone. No typical "mini brain" sign, calcification and tumor bone were observed. MRI showed that T10 vertebral body presented hypointensity on T1WI, mild hyperintensity on T2WI and FLAIR. The lesion was markedly enhanced on enhanced MRI scan. No paraspinal mass and abscess were detected. The intervertebral disc signal and shape were normal. A plasma cell neoplasm was suspected in surgical pathology exam. The lesion was ultimately diagnosed as SBP by combining imaging features, laboratory M protein, blood calcium and creatine level. Conclusions SBP in thoracic vertebrae occurs more frequently in the anterior part of vertebral body. Imaging features includes homogeneous, expansive and osteolytic destruction, with bone crest. The"mini brain"sign is valuable , but lack of sensitivity in diagnosis. The diagnosis of SBP should combine with imaging features, clinical laboratory and pathological exam results.
Keywords：Solitary plasmacytoma of boneTomographyX-ray computedMagnetic resonance imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 76-80 )