Study progress of multimodal MRI in basalganglia-thalamocortical circuit of idiopathic generalized epilepsy
Lv Guiwen
FAN Guoguang
Abstract：Idiopathic generalized epilepsy is a group of epileptic disorders without structural brain abnormalities and clear pathogeny of epilepsy syndrome. The etiology is still unknown. Previous studies have speculated that thalamocortical circuit plays an important role. Currently through the research of new MR technologies, the basalganglia-thalamocortical circuit is considered to be responsible for the generation and propagation of seizures. Conventional MRI can ’t detect abnormalities, but multimodal new MRI technologies of diffusion tensor imaging, voxel based morphometry and resting-state functional MRI can find abnormal changes in this circuit from structure, volume and function. In this paper, we reviewed the recent progress of those MRI technologies.
Keywords：Idiopathic generalized epilepsyDiffusion tensor imagingVoxel based morphometryResting -state functional MRI
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 505-508 )