Three dimensional speckle tracking technique in the evaluation of acute coronary syndrome patients after percutaneous coronary intervention

ZHANG Qinghua; LI Yanping

doi:10.19300/j.2016.L3887

Abstract：Objective To evaluate the changes of left ventricular function in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) treatment by using three-dimensional speckle tracking echocardiography ( 3D-STE ) technique . Methods Eighty-three patients with ACS treated by PCI from March 2014 to March 2015 underwent ultrasound echocardiography diagram with and without 3D-STE before and 7, 30, 90, and 180 days after PCI treatment. We used conventional ultrasound echocardiography diagram to evaluate patient’s heart rate and left atrial diameter, left ventricular diameter, and thickness of interventricular septum; and used 3D-STE to evaluate the left ventricular global longitudinal peak systolic strain (LVGLS), left ventricular global circular peak systolic strain (LVGCS), left ventricular global radial peak systolic strain (LVGRS), left ventricular end diastolic volume (LVEDV), left ventricular end systolic diastolic volume (LVESV), and left ventricular ejection fraction (LVEF). Sixty cases of healthy subjects were selected as the control group. By using repeated measures analysis of variance and LSD Post-hoc comparisons we compared the heart function among different time points of exams in patients and between patients and controls. Results The heart rate, left atrial diameter, and left ventricular diameter before and 7,30,90 days after PCI treatment were significantly higher in the patient group than the control group (P<0.05). After PCI treatment, the patient’s heart rate, left atrial diameter, left ventricular anterior and posterior diameter gradually dropped to the lowest point at 90 days after PCI treatment (P<0.05). The LVGLS, LVGCS, LVGRS, and LVEF gradually increased, the LVEDV and LVESV gradually decreased. the highest/lowest point was reached at 180 days after PCI treatment. Compared with the control group, the LVGLS, LVGCS, LVGRS, and LVEF at different times were significantly lower than the measure in the control group, while LVEDV and LVESV were significantly higher than the measure in the control group (P<0.05). Conclusions The cardiac left ventricular function of ACS patients was significantly lower than that of normal people. PCI treatment can improve cardiac function, but not to the normal level. Three dimensional speckle tracking technique can be used to evaluate left ventricular function in patients with ACS after PCI.