Research progresses of diffusion weighted and molecular MR imaging in microenvironment of ovarian tumors
YIN Bing
LI Wenhua
Abstract：Ovarian cancers, as common malignant tumors in female reproductive system, are difficult to be detected in early phase and are diagnosed in mid-late stage in most cases, often accompanied with peritoneal metastasis, which results in a difficulty of complete resection and a high recurrence rate. These conditions are closely linked to the unclearness of a series of mechanisms that trigger tumor growth, initiate tumor angiogenesis, promote tumor migration and invasion and facilitate immune evasion in the tumor microenvironment composed by tumor cells, tumor matrix, inflammatory cells and stromal cells. Studying and estimating ovarian tumor microenvironment in a dynamic, multivariant and noninvasive way with structural, functional and molecular imaging methods together is of great importance to monitor biological behavior and therapeutic effect of ovarian tumors and to judge tumor prognosis.
Keywords：Ovarian tumor microenvironmentDiffusion weighted imagingMolecular imagingCell densityMicrovessel densityTumor associated macrophageFolate receptor
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 242-245 )